ABSTRACT
The present study reveals the inhibitory effect of iron intoxication on the process of dentine mineralization. Wistar rats were injected intraperitoneally with iron dextran at 0.88 g/kg body weight per day for 10 days during the period of odontogenesis. An age-matched group was injected intraperitoneally with bisodium etidronate (EHBP) at 20 mg/kg body weight per day for 10 days. Another age-matched group was treated with similar amounts of saline intraperitoneally and considered as control. At the end of the experimental period the animals intoxicated with iron exhibited non-mineralized dentine and mineralized bone. The animals treated with EHBP showed non-mineralized dentine and bone. These findings would suggest the existence of different mineralization mechanisms for bone and dentine.
Subject(s)
Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Intensive Care Units , Wounds and Injuries/therapy , Wounds and Injuries/diagnosisSubject(s)
Humans , Enteral Nutrition , Parenteral Nutrition, Total , Intensive Care Units , VenezuelaSubject(s)
Humans , Dextrans , Homeostasis , Hyponatremia , Osmotic Pressure , Saline Solution, HypertonicABSTRACT
Se realiza un estudio retrospectivo en 975 historias clínicas de pacientes egresados del Servicio de Cirugía General del I.N.S.N. entre 1979 y 1983 con el diagnóstico de apendicitis aguda, con la finalidad de determinar la incidencia de absceso residual intraabdominal postapendicectomía y algunos factores predisponentes asi como su morbimortalidad. Se encontró una incidencia de 6.1% de A.R.I. postapendicectomía la que aumenta significativamente pasadas las 24 horas de enfermedad y al no invaginar el muñon apendicular. El 94.9% de los casos de A.R.I. presentó perforación del apéndice y el 62% peritonitis generalizada. Su localización mas frecuente fue el fondo de saco de Douglas y sólo tres pacientes no recibieron antibióticos en el postoperatorio. Fallecieron dos pacientes (3.38% )